Building Healthy Communities

Martin Mwita, who just turned 21, recently became the first patient in the St. Louis region to receive a gene therapy newly approved by the Food and Drug Administration (FDA) for sickle cell disease. Washington University School of Medicine in St. Louis and St. Louis Children’s Hospital are among only a few academic medical centers in the U.S. that have begun offering the treatment.

Siteman Cancer Center at Barnes-Jewish Hospital and WashU Medicine has been ranked No. 13 of cancer centers nationwide by Newsweek. The recognition — part of the news magazine’s listing of America’s Best Hospitals for Specialized Care 2025 — makes Siteman the highest-ranked cancer center in Missouri, Illinois and beyond.

The Clinical Research Training Center (CRTC) TL1 program recently partnered with the Center for Community Health Partnership & Research (CCHPR) for an impactful day of community engagement. Serving as a Social Determinants of Health (SDOH) session, this four-hour retreat encouraged two-way learning and building stronger community-academic ties.

On May 16, 2025, Centennial Christian Church in St. Louis, a longtime community partner of Washington University School of Medicine in St. Louis, was devastated by an EF-3 tornado. Tragically, community leader Patricia Penelton lost her life, and fellow advocate Sherrill Jackson sustained injuries. Despite the destruction, the church and its partners including WashU’s Center for Community Health Partnership & Research (CCHPR) remain committed to rebuilding and continuing their mission of service and community engagement.

Last year, with funding from the Gephardt Institute’s St. Louis Impact Fund, three students at the WashU School of Medicine hosted a series of workshops aimed at helping St. Louis seniors take a more active role in their own health and well-being. 

Community engagement is woven into the fabric of WashU Medicine. Guided by a deep commitment to helping others, many faculty have built lasting community partnerships that drive innovative care, education and community-engaged research. In April, 55 faculty members at WashU Medicine were honored with 2025 Dean’s Impact Awards, which recognized individuals whose dedicated service and leadership have left a lasting mark across WashU Medicine’s mission areas. These honorees represent the compassion, innovation and dedication required to build meaningful community-focused change. 

As temperatures continue to warm and the days become longer, St. Louisans are ready to get outside. And as part of its “In St. Louis, For St. Louis” commitment, WashU is supporting several organizations focused on outdoor recreation.

Amy Eyler, a professor at WashU’s Brown School, is leading a new initiative to advance research on the health benefits of spending time in nature and address the social and environmental barriers that limit access to green spaces in underserved communities. Eyler, along with co-principal investigator Derek Hoeferlin, professor and chair of landscape architecture at the Sam Fox School of Design & Visual Arts, have received a $50,000 IGNITE interdisciplinary grant through WashU’s Here and Next initiative. The grant helped launch the Nature and Health Alliance at WashU, a collaboration that brings together faculty, community organizations in St. Louis, and national partners to explore how exposure to nature can enhance physical and mental well-being.

Shannon Lenze, PhD, an associate professor of psychiatry at Washington University School of Medicine in St. Louis, knows the grim statistics showing that gun violence, racism, poverty and a lack of access to transportation and nutritious foods can adversely affect mental and physical health during pregnancy, particularly among Blacks who suffer disproportionately more than people of other races. However, Lenze noted that many obstetricians hesitated to question pregnant patients about trauma related to their life experiences because it could upset them. Through her partnership with Elevating Voices, Addressing Depression, Toxic Stress and Equity (EleVATE) a community of academic physicians and clinics in St. Louis, Lenze had a light bulb moment — one that has helped guide her research on prenatal health of the pregnant person and baby.

The Washington University School of Medicine in St. Louis Undiagnosed Diseases Network (UDN) Diagnostic Center of Excellence was established in 2019 to solve the trickiest medical mysteries in Missouri and nearby states. Now, the center is expanding. Buoyed by the renewal of the center’s five-year, $3.8 million grant, the UDN leadership team plans to increase outreach to medically underserved communities and increase capacity from 30 to 50 patients a year. The center has established a collaboration with the St. Louis Integrated Health Network, an organization dedicated to improving the quality, accessibility and affordability of health care.